In a small bowl, whisk together the buttermilk, garlic powder, Italian seasonings, ground red pepper, and salt until combined.
Pour the buttermilk mixture into a large zip-top bag or baking dish. Add the chicken pieces, ensuring they are well coated. Seal the bag or cover the dish and refrigerate for at least 2 hours or overnight.
About 30 minutes before cooking, remove the chicken from the refrigerator.
If grilling, preheat the grill to medium-low heat. Discard the marinade and place the chicken on the grill, cooking for about 30-40 minutes until golden brown and cooked through.
If baking, preheat the oven to 450°F (232°C). Arrange the chicken in a single layer in an oven-safe skillet or baking pan. Bake for about 30 minutes or until the internal temperature reaches 165°F (74°C).
Let the chicken rest for a few minutes before serving.
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Notes
Store leftovers in an airtight container in the refrigerator for up to 3 days.