Brush the salmon fillets lightly with olive oil or melted butter.
In a bowl, combine smoked paprika, garlic powder, onion powder, salt, oregano, thyme, pepper, and cayenne pepper to create the spice rub. Set aside 2 tablespoons for the sauce.
Rub the spice blend generously over the salmon fillets.
Heat 1 tablespoon of olive oil in a large skillet over medium-high heat. Add the salmon and cook for about 4 minutes until crispy. Flip and cook for another 3-6 minutes until cooked through. Remove and cover with foil.
In the same skillet, add more oil if needed and sauté chopped red onions for about 3 minutes until translucent.
Add chopped bell peppers, minced garlic, and the reserved spice mix. Cook for another 2 minutes until tender.
Pour in half of the chicken broth. Mix the remaining broth with cornstarch until smooth and add to the skillet, stirring well.
Add heavy cream and fire-roasted diced tomatoes, bringing the mixture to a gentle simmer until thickened.
Stir in Parmesan cheese until melted, then add lime juice.
Return cooked salmon to the skillet, warming it in the sauce for about a minute. Season to taste with salt, pepper, or cayenne.
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Notes
Store leftovers in the refrigerator for up to 3 days.