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High-Protein Spinach and Artichoke Chicken Casserole

This high-protein spinach and artichoke chicken casserole features tender chicken in a creamy sauce with nutritious spinach and artichokes, making it a comforting dish packed with flavor and health benefits.
Prep Time 15 minutes
Cook Time 30 minutes
Total Time 45 minutes
Course Main Course
Cuisine American
Servings 6 servings
Calories 400 kcal

Ingredients
  

Main ingredients

  • 2 cups cooked, shredded chicken
  • 1 cup fresh or frozen spinach, thawed and drained Ensure the spinach is well drained to avoid excess moisture.
  • 1 can (14 oz) artichoke hearts, drained and chopped
  • 1 cup Greek yogurt
  • 1 cup cream cheese, softened
  • 1 cup shredded mozzarella cheese Divided for layering.
  • 1 cup shredded Parmesan cheese Divided for layering.
  • 1 tablespoon minced garlic
  • 1 teaspoon onion powder
  • 1 teaspoon salt
  • 1/2 teaspoon pepper
  • 1/2 teaspoon red pepper flakes (optional) For a bit of heat.
  • 1 tablespoon olive oil For greasing the baking dish.
  • 1/2 teaspoon dried Italian herbs

Instructions
 

Preparation

  • Preheat your oven to 350°F (175°C).
  • In a large mixing bowl, combine the shredded chicken, spinach, chopped artichokes, Greek yogurt, cream cheese, half of the mozzarella, and half of the Parmesan. Stir until well mixed.
  • Add the minced garlic, onion powder, salt, pepper, and red pepper flakes (if using). Mix thoroughly to ensure all ingredients are well distributed.
  • Lightly grease a 9x13-inch baking dish with olive oil. Pour the mixture into the dish, spreading it evenly.

Baking

  • Sprinkle the remaining mozzarella and Parmesan cheese over the top of the casserole.
  • Bake for 25-30 minutes, or until the cheese is melted and bubbly.
  • Remove from the oven and let it cool for a few minutes before serving.

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Notes

Serve directly from the baking dish or on individual plates. Pair with a side salad or whole grain bread for a complete meal. Garnishing with fresh herbs can enhance presentation and flavor.
Keyword Chicken Casserole, Comfort Food, High Protein, Meal Prep, spinach and artichoke