Activate the sauté function on the Instant Pot. Add the ground beef (or turkey) and cook until browned, about 5-7 minutes. Drain excess grease if necessary.
Turn off the sauté function. Add water, Italian seasoning, garlic powder, salt, and black pepper, stirring to combine.
Break the spaghetti noodles in half and lay them in the pot in different directions to prevent sticking.
Pour the tomato sauce and marinara sauce over the noodles. Do not stir.
Close the lid and set the steam valve to sealing. Cook on high pressure for 7 minutes for regular spaghetti or 5 minutes for whole wheat spaghetti.
Once cooking is complete, perform a quick release by carefully moving the steam valve to venting.
Open the lid and stir the spaghetti gently to combine with the sauce. Let it rest for 3-5 minutes before serving.
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Notes
Store leftovers in an airtight container in the fridge for 3-5 days or freeze for up to 3 months.